With the European population growing older, the challenge is to keep an increasing number of seniors across all European countries healthy and active. In Europe, between 13.5 % and 29.7 % of older adults living at home are malnourished or at risk of protein energy malnutrition. PROMISS aims to better understand and ultimately prevent protein energy malnutrition in seniors. Thereby, PROMISS will contribute to improve active and healthy ageing.

Project information

Nutrition for healthy ageing


16th September 2021

Watch the PROMISS final conference on Youtube!

It is now possible to make the recordings of our final event available to the wide public!

Click here to retrieve all the excellent contents and good memories of PROMISS!

29th August 2021

Publications overview by year










27th August 2021

Prospective associations of protein intake parameters with muscle strength and physical performance in community-dwelling older men and women from the Quebec NuAge cohort

Hengeveld LM, Chevalier S, Visser M, Gaudreau P, Presse N.

Am J Clin Nutr. 2021 Apr 6;113(4):972-983. doi: 10.1093/ajcn/nqaa360.


Dietary protein has been related to muscle function in aging. Beyond total intake, parameters such as protein distribution across meals might also be important.

The research aimed to examine prospective associations of different protein intake parameters with muscle strength and physical performance in community-dwelling older men and women.

In total, 524 men and 574 women aged 67-84 y at baseline (T1) were followed annually for 3 y (T2, T3, T4). Outcomes included handgrip strength (kPa), knee extensor strength (kg), and physical performance (Timed Up and Go, s) at T4, and their 3-y changes (T4 minus T1). Protein intake parameters were assessed using nine 24-h recalls collected over 3 y (T1, T2, T3) and included daily total intake (g/d), number of protein-providing meals and snacks, and protein distribution across meals (expressed as CV). Associations were examined by multivariable linear regression models including all protein intake parameters simultaneously. Also, the optimal protein dose (g) per meal for the maximum effect size of total daily intake was determined.

Results: Higher daily protein intake was associated with better knee extensor strength and physical performance at T4 in both sexes and less physical performance decline in women. Optimal protein doses per meal were 30-35 g in men and 35-50 g in women for these outcomes. In men, more uneven protein distribution was associated with better physical performance at T4 and less handgrip strength decline. In women, a higher number of protein-providing snacks was associated with better handgrip strength and knee extensor strength at T4 and less handgrip strength decline. In neither sex was number of protein-providing meals associated with outcomes.

Conclusions: Higher daily protein intake, up to 30-50 g protein/meal, may contribute to better knee extensor strength and physical performance in generally well-functioning older men and women. More aspects of protein intake may contribute to muscle strength and physical performance than solely the daily quantity, notably the protein dose per meal.

Access the full article here.

View all news


🇮🇹 💡 Una tabella delle proteine può aiutarti a tenere il conto della quantità di proteine che mangi. ⏬ È possibile scaricarne uno dal sito Web PROMISS: promiss-vu.eu/community/olde… pic.twitter.com/FX1evp4NDC

About 3 days ago from PROMISS Project's Twitter via TweetDeck

View all Tweets